Skip to content

42年を経てHoFH診断に至った症例

3歳時に黄色腫を認めFHと診断、その後、45歳時に遺伝学的検査で LDL受容体に変異を有するFHホモ接合体(複合ヘテロ接合体)と診断されたHoFH患者に対するエヴキーザ®のLDL-Cに変化が認められた1例

松田 高明 先生 (筑波大学附属病院 内分泌代謝・糖尿病内科)

What is EVKEEZA used for?

EVKEEZA (evinacumab) is used to treat adults and children aged 5 years and older with very high cholesterol caused by a condition called homozygous familial hypercholesterolemia (HoFH). EVKEEZA is used with a low-fat diet and other medicines to bring down cholesterol levels.

Do not use EVKEEZA if:

  • You are allergic to evinacumab or any of the other ingredients in this medicine

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take EVKEEZA. Talk about any health conditions or problems you may have, including:

  • If you are pregnant, think you might be pregnant, or plan to become pregnant, ask your healthcare professional for advice before taking EVKEEZA. EVKEEZA may harm your unborn baby. Tell your healthcare professional if you become pregnant while using EVKEEZA. For people who are able to become pregnant:
    • Your healthcare professional may do a pregnancy test before you start treatment with EVKEEZA.
    • You should use an effective method of birth control during treatment and for at least 5 months after the last dose of EVKEEZA. Talk to your healthcare professional about birth control methods that you can use during this time.
  • If you are breastfeeding or plan to breastfeed, ask your healthcare professional for advice before you are given EVKEEZA. It is not known if EVKEEZA passes into your breast milk. You and your healthcare professional should decide if you will receive EVKEEZA or breastfeed.

Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements, or alternative medicines.

  • Studies to test how EVKEEZA interacts with other drugs have not been done.